The Lou Gehrig Society is dedicated to honoring the legacy of baseball giant Lou Gehrig by offering targeted scholarships and grants that promote public health, wellness and integrity in America.

Over a 14-season span from 1925-1939, Lou played in 2,130 consecutive games, the streak ending only when Lou became disabled and too weak to play. After his diagnosis of amyotrophic lateral sclerosis (now known as Lou Gehrig's Disease), he came under the care of Dr. Caldwell B. Esselstyn who oversaw Lou's health every day for his remaining two years. Their friendship deepened, and Lou's widow Eleanor left a large portion of her estate to The Rip Van Winkle Foundation (, an organization Dr. Esselstyn had established in New York State's Columbia County. The Rip Van Winkle Foundation continues to focus on identifying policies, techniques and programs that prevent disease. As a tribute to Lou, the Foundation launched The Lou Gehrig Society in 2011.

The Rip Van Winkle Foundation, d/b/a/ The Lou Gehrig Society, owns the property rights to the image, name, and voice of Lou Gehrig, and all trademarks protecting his words and signature. Any use of the above without written consent of the Foundation is strictly prohibited.